Gastroesophageal reflux, commonly known as acid reflux, is a benign physiologic process for all individuals in which stomach contents back flow into the oesophagus. It usually occurs post-prandial, is brief and does not cause bothersome symptoms. Gastroesophageal reflux disease (GERD) occurs when acid reflux causes symptoms which impair quality of life and/or lead to complications. Such symptoms include heartburn and acid regurgitation.

In most cases, lifestyle modification alone is insufficient. For mild cases, over-the-counter products such as antacids, alginates and histamine-2 receptor antagonists (H2RAs) are safe and effective first line treatments.Patients with unpredictable symptoms of GERD will likely benefit from alginates or antacids taken as needed when symptoms occur. 

Antacids are a group of medicines which work by lowering acidity in your stomach. Alginates react with saliva to form a foam barrier which floats on stomach contents to protect oesophagus from gastric acid. This will relieve symptoms of heartburn, gastric reflux and indigestion.

Gascovid Advance is a liquid formulation containing Potassium Bicarbonate  (antacid) and Sodium Alginate specially formulated for faster onset of action and lasting relief of heartburn symptoms. Potassium Bicarbonate is one of the strongest antacid and is non-constipating and less likely to cause diarrhoea compared to other formulations. 

Veragel-DMS is a chewable tablet containing Aluminium Hydroxide and Magnesium Carbonate Co-Precipitate (antacid), Dicyclomine (anti-spasmodic) and Dimethicone (anti-flatulent) for 3-in-1 action to relieve heartburn, stomach cramps and flatulence. 

Histamine-2-Receptor Antagonists (H2RAs) reversibly block histamine-2-receptors in the parietal cells to reduce acid production. Patients with predictable symptoms e.g. heartburn or reflux which occur after eating a large meal can be recommended H2RA such as famotidine, to be taken 30-60 minutes prior to the meal, to prevent or reduce acid reflux symptoms. 

Available in 2 strengths, Famotidine effectively reduces acid production in the stomach for short term relief of heartburn, dyspepsia and hyperacidity. It can also be prescribed for patients with mild – moderate and frequent symptoms, on top of Antacids for longer lasting symptom relief. 

Treatment of moderate to severe GERD requires acid suppression with either Proton Pump Inhibitors (PPIs) or H2RAs. PPIs have been shown to be superior to H2RAs in keeping the pH of gastric acid above four for prolonged periods of time and providing more healing and symptomatic relief. Four to eight weeks of PPI once daily dosing is recommended as first line in patients with moderate/severe and persistent symptoms of GERD. Most patients would require a long term maintenance therapy due to the high likelihood of recurrence in the absence of maintenance therapy.

Proton pump inhibitors inhibit proton pumps of gastric parietal cells to decrease gastric acid secretion and allow healing of oesophagus.

 

Duonazole (Pantoprazole) is a PPI which is shown to be 91% more effective than Ranitidine  (H2RA) in healing GERD andcontributes to 43% more GERD symptom-free days than Ranitidine. Patients taking Duonazole experiences lesser symptoms relapse and fewer symptomatic episodes 1 week after stopping therapy compared with esomeprazole. Duonazole has also the least interactions with commonly used drugs or drugs with narrow therapeutic window. 

Omezole (Omeprazole) is the one of the longest available PPI available and has been actively prescribed for the treatment and prevention of GERD and Peptic Ulcer Disease (PUD). It is well tolerated and is a potent acid suppression agent.

Prozyme is a complete digestive tablet which is used as a supplementary therapy to restore digestive efficiency as it consists of digestive enzymes which breaks down carbohydrates, protein and fats for better absorption of nutrients. Enriched with Vitamin B complex and Peppermint oil, Prozyme assists with utilisation of nutrients and soothes smooth muscles and abdominal discomfort in the GI tract. Prozyme also contains Probiotics and Prebiotics which promotes an ideal balance of gut flora, keep the gut healthy and is your all-in-one digestive aid.

Gastroesophageal reflux, commonly known as acid reflux, is a benign physiologic process for all individuals in which stomach contents back flow into the oesophagus. It usually occurs post-prandial, is brief and does not cause bothersome symptoms. Gastroesophageal reflux disease (GERD) occurs when acid reflux causes symptoms which impair quality of life and/or lead to complications. Such symptoms include heartburn and acid regurgitation.

In most cases, lifestyle modification alone is insufficient. For mild cases,  antacids, alginates and histamine-2 receptor antagonists (H2RAs) are safe and effective first line treatments. Patients with unpredictable symptoms of GERD will likely benefit from alginates or antacids taken as needed when symptoms occur. Antacids are a group of medicines which work by lowering acidity in your stomach. Alginates react with saliva to form a foam barrier which floats on stomach contents to protect oesophagus from gastric acid. This will relieve symptoms of heartburn, gastric reflux and indigestion.

Gascovid Advance is a liquid formulation containing Potassium Bicarbonate  (antacid) and Sodium Alginate specially formulated for faster onset of action and lasting relief of heartburn symptoms. Potassium Bicarbonate is one of the strongest antacid and is non-constipating and less likely to cause diarrhoea compared to other formulations. 

Veragel-DMS is a chewable tablet containing Aluminium Hydroxide and Magnesium Carbonate Co-Precipitate (antacid), Dicyclomine (anti-spasmodic) and Dimethicone (anti-flatulent) for 3-in-1 action to relieve heartburn, stomach cramps and flatulence. 

Histamine-2-Receptor Antagonists (H2RAs) reversibly block histamine-2-receptors in the parietal cells to reduce acid production. Patients with predictable symptoms e.g. heartburn or reflux which occur after eating a large meal can be recommended H2RA such as famotidine, to be taken 30-60 minutes prior to the meal, to prevent or reduce acid reflux symptoms. 

Available in 2 strengths, Famotidine effectively reduces acid production in the stomach for short term relief of heartburn, dyspepsia and hyperacidity. It can also be prescribed for patients with mild – moderate and frequent symptoms, on top of Antacids for longer lasting symptom relief. 

Treatment of moderate to severe GERD requires acid suppression with either Proton Pump Inhibitors (PPIs) or H2RAs. PPIs have been shown to be superior to H2RAs in keeping the pH of gastric acid above four for prolonged periods of time and providing more healing and symptomatic relief. Four to eight weeks of PPI once daily dosing is recommended as first line in patients with moderate/severe and persistent symptoms of GERD. Most patients would require a long term maintenance therapy due to the high likelihood of recurrence in the absence of maintenance therapy.

Proton pump inhibitors inhibit proton pumps of gastric parietal cells to decrease gastric acid secretion and allow healing of oesophagus.

 

Duonazole (Pantoprazole) is a PPI which is shown to be 91% more effective than Ranitidine  (H2RA) in healing GERD and contributes to 43% more GERD symptom-free days than Ranitidine. Patients taking Duonazole experiences lesser symptoms relapse and fewer symptomatic episodes 1 week after stopping therapy compared with esomeprazole. Duonazole has also the least interactions with commonly used drugs or drugs with narrow therapeutic window. 

Omezole (Omeprazole) is the one of the longest available PPI available and has been actively prescribed for the treatment and prevention of GERD and Peptic Ulcer Disease (PUD). It is well tolerated and is a potent acid suppression agent

 

Prozyme is a complete digestive tablet which is used as a supplementary therapy to restore digestive efficiency as it consists of digestive enzymes which breaks down carbohydrates, protein and fats for better absorption of nutrients. Enriched with Vitamin B complex and Peppermint oil, Prozyme assists with utilisation of nutrients and soothes smooth muscles and abdominal discomfort in the GI tract. Prozyme also contains Probiotics and Prebiotics which promotes an ideal balance of gut flora, keep the gut healthy and is your all-in-one digestive aid.